Zinc-MNP Trial for Prevention of Diarrhea and Promotion of Linear Growth

NACompletedINTERVENTIONAL
Enrollment

2,886

Participants

Timeline

Start Date

February 20, 2018

Primary Completion Date

January 12, 2020

Study Completion Date

January 12, 2020

Conditions
DiarrheaStunting
Interventions
DIETARY_SUPPLEMENT

Standard MNP

Standard MNP, 15 micronutrients (Vitamin A 400 µg, vitamin D 5 µg, vitamin E 5 mg, vitamin C 30 mg, thiamine 0.5 mg, riboflavin 0.5 mg, niacin 6 mg, pyridoxine 0.5 mg, vitamin B12 0.9 mg, folate 150 µg, iron 10 mg, zinc 4.1 mg, copper 0.56 mg, selenium 17.0 µg and iodine 90 µg). Daily supplementation for 24 weeks.

DIETARY_SUPPLEMENT

High zinc, low iron MNP

Same as group 1, except with 10 mg zinc instead of 4.1 mg and 6 mg iron instead of 10 mg. Daily supplementation for 24 weeks.

DIETARY_SUPPLEMENT

High zinc, low/no iron on alternating days

Same as study group 1, except with 10 mg zinc instead of 4.1 mg, and 6 mg iron and no iron on alternating days instead of 10 mg. Daily supplementation for 24 weeks.

DIETARY_SUPPLEMENT

Dispersible zinc supplement

10 mg zinc in a dispersible tablet. Daily supplementation for 24 weeks.

DIETARY_SUPPLEMENT

Intermittent zinc supplement

10 mg zinc in a dispersible tablet. Daily supplementation for 14 days at baseline and 3 months, placebo tablet on all other days.

DIETARY_SUPPLEMENT

Placebo powder

Daily provision of a placebo powder for 24 weeks.

Trial Locations (1)

Unknown

Icddr,B, Dhaka

All Listed Sponsors
collaborator

International Centre for Diarrhoeal Disease Research, Bangladesh

OTHER

collaborator

Johns Hopkins Bloomberg School of Public Health

OTHER

collaborator

University of Colorado, Denver

OTHER

lead

UCSF Benioff Children's Hospital Oakland

OTHER

NCT03406793 - Zinc-MNP Trial for Prevention of Diarrhea and Promotion of Linear Growth | Biotech Hunter | Biotech Hunter