A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy

PHASE2CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

April 4, 2018

Primary Completion Date

March 10, 2020

Study Completion Date

March 10, 2020

Conditions
Muscular DystrophiesMuscular Dystrophy, DuchenneMuscular Disorders, AtrophicMuscular DiseasesNeuromuscular DiseasesNervous System DiseasesGenetic Diseases, X-LinkedGenetic Diseases, Inborn
Interventions
BIOLOGICAL

CAP-1002

The active pharmaceutical ingredient in CAP-1002 is Cardiosphere-Derived Cells (CDCs). CDCs are known to secrete numerous bioactive elements (growth factors, exosomes) which impact the therapeutic benefits of the cell-based therapy. The mechanism of action is the composite ability to be immunomodulatory, anti-fibrotic, anti-inflammatory, and pro-angiogenic.

DRUG

Placebo

Placebo

Trial Locations (9)

32827

Nemours Children's Hospital, Orlando

45229

Cincinnati Children's Hospital Medical Center, Cincinnati

52242

University of Iowa, Iowa City

53226

Children's Hospital Wisconsin, Milwaukee

63110

Washington University, St Louis

80045

Children's Hospital Colorado, Aurora

84112

University of Utah, Salt Lake City

95817

University of California, Davis, Sacramento

01655

University of Massachusetts Medical Center, Worcester

All Listed Sponsors
lead

Capricor Inc.

INDUSTRY

NCT03406780 - A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy | Biotech Hunter | Biotech Hunter