Fasciectomy vs Collagenase Injection in Recurrent Dupuytren Disease

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

March 20, 2018

Primary Completion Date

September 1, 2024

Study Completion Date

September 30, 2027

Conditions
Dupuytren Disease of Finger
Interventions
PROCEDURE

Fasciectomy

Surgical excision of Dupuytren cords causing finger joint contractures. Surgery done under regional or general anesthesia. Additional procedures (such as capsulotomy or skin graft) done if surgeon deemed necessary.

DRUG

Collagenase Clostridium Histolyticum

Injection of Collagenase into the Dupuytren cord after local anesthesia (nerve block) followed 24-48 hours later by finger manipulation after local anesthesia

Trial Locations (1)

SE 28125

Department of Orthopedics Hässleholm-Kristianstad, Hässleholm

All Listed Sponsors
lead

Region Skane

OTHER