50
Participants
Start Date
February 14, 2018
Primary Completion Date
October 28, 2019
Study Completion Date
October 28, 2019
Preoperative Stroke Volume(SV)-guided fluid optimization
"Preoperative SV-guided hemodynamic optimization will be commenced with patients receiving 250ml fluid challenges over five minutes aiming to maximize SV. Maximal SV is defined as absence of a sustained rise in SV by at least 10% in response to a fluid challenge.~PPI will be obtained from the Masimo Radical 7 (Masimo, Irvine, CA, USA) and NIRS from Invos 5100C (Medtronic, Minneapolis, MN, USA).~BV measurements will use pulse dye densitometry (PDD) with Indocyanine Green (ICG). We will use the Dye Densitogram 3300 analyser Nihon Kohden (Tokyo, Japan) for registration of the spectrophotometrical absorption of ICG and calculation of BV."
Department af Anesthesia, Hvidovre Hospital, Hvidovre
Hvidovre University Hospital
OTHER