Pre-operative Stereotactic Radiosurgery Followed by Resection for Patients With Brain Metastases

NACompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

March 26, 2018

Primary Completion Date

August 26, 2022

Study Completion Date

May 21, 2024

Conditions
Brain Metastases
Interventions
PROCEDURE

Radiosurgery

"Stereotactic radiosurgery will be delivered on all patients utilizing gamma knife or linear accelerator based techniques as per RTOG-9005 dosing criteria (Section 11 Table 1) based on tumor diameter with the exception that the largest lesion diameter to be treated with 15 Gy will be 5 cm. All apparent, previously untreated brain metastases will be treated with radiosurgery at this time.~Radiosurgery will be performed 1-4 days prior to surgical resection. Vital signs and MRI Brain planning scan will be performed on the day of radiosurgery prior to the procedure."

Trial Locations (3)

46202

Indiana University Health Hospital, Indianapolis

Indiana University Health Methodist Hospital, Indianapolis

Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis

All Listed Sponsors
lead

Indiana University

OTHER

NCT03398694 - Pre-operative Stereotactic Radiosurgery Followed by Resection for Patients With Brain Metastases | Biotech Hunter | Biotech Hunter