Effects of Hyperbaric Oxygen (HBO) on Blood Count Recovery After Autologous Hematopoietic Stem Cell (HSPC) Transplant for Multiple Myeloma

PHASE2CompletedINTERVENTIONAL
Enrollment

99

Participants

Timeline

Start Date

May 10, 2018

Primary Completion Date

September 30, 2022

Study Completion Date

March 28, 2023

Conditions
Myeloma
Interventions
BIOLOGICAL

Hyperbaric Oxygen Therapy

The intervention consists of exposure to hyperbaric oxygen at 2.5 atmospheres absolute (ATA) for a total of 2 hours, in a single see-through hyperbaric chamber, breathing 100% oxygen for 90 minutes while subjects are resting in supine position. During the 2 hours, there will be compression and decompression phases for 15 minutes each in which subjects will be breathing compressed environmental air (21% oxygen).

OTHER

No Hyperbaric Oxygen Therapy

The reference arm will not receive hyperbaric oxygen therapy prior to hematopoietic stem cell transplant.

Trial Locations (3)

14642

Wilmot Cancer Institute, University of Rochester Medical Center, Rochester

40536

University of Kentucky Markey Cancer Center, Lexington

66205

The University of Kansas Cancer Center, Fairway

All Listed Sponsors
lead

Omar Aljitawi

OTHER

NCT03398200 - Effects of Hyperbaric Oxygen (HBO) on Blood Count Recovery After Autologous Hematopoietic Stem Cell (HSPC) Transplant for Multiple Myeloma | Biotech Hunter | Biotech Hunter