PEF-Block & Ribs Fractures

NACompletedINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

June 18, 2018

Primary Completion Date

June 15, 2022

Study Completion Date

June 15, 2022

Conditions
Chest Trauma With Ribs Fractures
Interventions
PROCEDURE

Intravenous morphine patient-controlled analgesia (PCA)

"Group 1 control:~* Morphine titration at 0.1 mg/kg~* Establishment of PCA morphine:~* concentration 1mg/ml~* 1ml bolus~* refractory period of 7 minutes~* no maximum dose per day. Premedication of the patient with Ketamine 0.15 mg/kg and Propofol 0.5 mg /kg"

PROCEDURE

Block of the posterior exo-thoracic fascia with Ropivacaine

"Group 2 PEF block:~* Establishment of PCA morphine:~* concentration 1mg / ml~* 1ml bolus~* refractory period of 7 minutes~* no maximum dose per day.~* Realization of a block of the posterior exo-thoracic fascia (PEF block) at the median level of ribs fractures with ropivacaine 5mg / mL, 3 mg / kg under echography guidance. ALR needle (type neurostimulation) with a length of 100 mm is used. When the injection is performed an analgesia catheter is deposited in the space created by local anesthetics. Realization of ropivacaine bolus 2mg / ml at 0.1ml/kg every 4 hours. Possibility of an additional bolus of 0.1ml / kg every hour if insufficient analgesia."

PROCEDURE

Block of paravertebral space with Ropivacaine

"Group 3 paravertebral block:~* Establishment of PCA morphine:~* concentration 1mg / ml~* 1ml bolus~* refractory period of 7 minutes~* no maximum dose per day.~* Realization of a paravertebral block (BPV) at the median level of ribs fractures ropivacaine 5mg / mL, (0.3ml / kg) 1.5 mg / kg under echography guidance. ALR needle (type neurostimulation) with a length of 100 mm is used. When the injection is performed an analgesia catheter is deposited in the space created by local anesthetics. Realization of bolus of ropivacaine 2mg / ml at 0.1ml / kg every 4 hours.~Possibility of an additional bolus of 0.1ml / kg every hour if insufficient analgesia.~In the case of failure of initial management with significant pain despite the iterative boli, epidural analgesia is used in recourse."

Trial Locations (1)

34295

University Hospital Center, Montpellier

All Listed Sponsors
lead

University Hospital, Montpellier

OTHER

NCT03396692 - PEF-Block & Ribs Fractures | Biotech Hunter | Biotech Hunter