Efficacy of Fish Oil or Olive Oil Supplementation on the Health Effects of Ozone Exposure in Healthy Young Subjects

PHASE1CompletedINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

December 18, 2017

Primary Completion Date

December 18, 2020

Study Completion Date

December 18, 2020

Conditions
HealthyDietary Supplement
Interventions
DRUG

Ozone

After the four-week supplementation period, each subject will be blindly exposed on consecutive days to filtered air for 2 hours and to 0.3 ppm ozone for 2 hours, while undergoing intermittent moderate exercise (minute ventilation of 20 L/min/m²).

DIETARY_SUPPLEMENT

Fish Oil

3 (1-gram) soft-gels daily Commercially available, enteric-coated, soft-gels formulated to deliver \>60% eicosapentaenoic/docosahexaenoic acids (EPA/DHA)

DIETARY_SUPPLEMENT

Olive Oil

3 soft-gels daily Commercially available soft-gels containing 1 gram of USDA organic certified, cold pressed, extra virgin, olive oil

Trial Locations (1)

27514

U.S. Environmental Protection Agency Human Studies Facility, Chapel Hill

All Listed Sponsors
collaborator

Environmental Protection Agency (EPA)

FED

lead

University of North Carolina, Chapel Hill

OTHER

NCT03395119 - Efficacy of Fish Oil or Olive Oil Supplementation on the Health Effects of Ozone Exposure in Healthy Young Subjects | Biotech Hunter | Biotech Hunter