205
Participants
Start Date
February 9, 2018
Primary Completion Date
November 26, 2019
Study Completion Date
February 28, 2020
vitamin C, vitamin B1, hydrocortisone
Vitamin C (1.5g) plus vitamin B1 (100mg) will be diluted in 100ml 0.9% NACL(normal saline) and administered IV every 6 hours for 4 days or until participant is discharged from the ICU. Hydrocortisone 50mg/ml will be administered via IV push over 1-2 minutes every 6hours for 4 days or until the patient is discharged from the ICU.
Normal saline
Normal saline (0.9% NaCl solution) volume to match all components
North Shore University Hospital, Manhasset
Long Island Jewish Hospital, New York
University Of Pittsburgh Medical Center, Pittsburgh
Beaumont Hospital, Royal Oak
Detroit Receiving Hospital, Detroit
Harper University Hospital, Detroit
Henry Ford Hospital, Detroit
Sinai Grace Hospital, Detroit
The University of Texas Health Science Center, Houston
Mayo Clinic - Arizona, Phoenix
Brigham and Women's Hospital, Boston
Beth Israel Deaconess Medical Center, Boston
Mount Auburn Hospital, Cambridge
Open Philanthropy
OTHER
Beth Israel Deaconess Medical Center
OTHER