Clinical Study to Investigate Effect of Macitentan on Riociguat Pharmacokinetics

PHASE1CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

January 9, 2018

Primary Completion Date

February 6, 2018

Study Completion Date

February 6, 2018

Conditions
Healthy Subjects
Interventions
DRUG

Riociguat (Adempas)

Riociguat film-coated tablets for oral administration at a strength of 1 mg

DRUG

Macitentan (Opsumit)

Macitentan film-coated tablets for oral administration at a strength of 10 mg

Trial Locations (1)

68167

CRS Clinical Research Services Mannheim, Mannheim

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Actelion

INDUSTRY