Non-invasive Neurally Adjusted Ventilatory Assist Versus Nasal Intermittent Positive Pressure Ventilation for Preterm Infants After Extubation

NACompletedINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

May 1, 2017

Primary Completion Date

April 30, 2019

Study Completion Date

April 30, 2019

Conditions
PrematurityRespiratory FailureVentilator Lung; Newborn
Interventions
DEVICE

NI-NAVA

"Enrolled infants will receive Surfactant and loading dose of Caffeine citrate prior to extubation. The criteria for extubation will be as per attending decision.~The device is used Servo-I ventilator (MAQUET). FiO 2 % is adjusted to maintain oxygen saturation between 90-94% on pulse oximetry. The flow rate is 8-10 L/min. NAVA electrodes will be inserted within nasogastric catheter \& positioned at the level of diaphragm.Vital signs and ventilatory parameters are monitored hourly. Blood gases will be measured before and one hour after extubation"

DEVICE

NIPPV

"Enrolled infants will receive Surfactant and loading dose of Caffeine citrate prior to extubation. The criteria for extubation will be as per attending decision.~The device is used Servo-I ventilator (MAQUET). FiO 2 % is adjusted to maintain oxygen saturation between 90-94% on pulse oximetry. The flow rate is 8-10 L/min. NAVA electrodes will be inserted within nasogastric catheter \& positioned at the level of diaphragm.Vital signs and ventilatory parameters are monitored hourly. Blood gases will be measured before and one hour after extubation"

Trial Locations (1)

21159

King Fahad Armed Forces Hospital, Jeddah

All Listed Sponsors
lead

King Fahad Armed Forces Hospital

OTHER_GOV

NCT03388437 - Non-invasive Neurally Adjusted Ventilatory Assist Versus Nasal Intermittent Positive Pressure Ventilation for Preterm Infants After Extubation | Biotech Hunter | Biotech Hunter