55
Participants
Start Date
January 5, 2017
Primary Completion Date
June 30, 2019
Study Completion Date
December 31, 2019
Exercise training
Combined aerobic and resistive training 3 times a week for 4 months. The strength training will be performed at moderate intensity (i.e., 50-60% of RM), and moderate volume (i.e., 2 to 3 sets per exercise). Endurance training will be performed at moderate- to high-intensity (i.e., 60-85% of VO2max) in the form of continuous and interval training (for high intensities), respectively. The training intensity will be prescribed individually on the basis of the initial exercise testing. Subjects will be thoroughly instructed on effective home-based exercise and advised to exercise in total 5 days a week.
omega 3 supplementation
Capsules with high content of omega 3 fatty acids (Calanus oil) will be taken every day with lunch meal. The content of omega-3 fatty acids (EPA, DHA) per day should reach 250 mg.
placebo
Capsules with content of omega 6 fatty acids (sunflower oil) will be taken every day with lunch meal.
Third Faculty of Medicine, Charles University, Prague
Charles University, Czech Republic
OTHER