Multi-Targeted Recombinant Ad5 (CEA/MUC1/Brachyury) Based Immunotherapy Vaccine Regimen in People With Advanced Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

11

Participants

Timeline

Start Date

January 31, 2018

Primary Completion Date

May 22, 2018

Study Completion Date

August 24, 2020

Conditions
NeoplasmsProstate CancerLung CancerBreast CancerColon Cancer
Interventions
BIOLOGICAL

ETBX-051; adenoviral brachyury vaccine

immunotherapeutic vaccine administered subcutaneously every 3 weeks for 3 doses, and then every 8 weeks for up to a year

BIOLOGICAL

ETBX-061; adenoviral Mucin-1 (MUC1) vaccine

immunotherapeutic vaccine administered subcutaneously every 3 weeks for 3 doses, and then every 8 weeks for up to a year

BIOLOGICAL

ETBX-011; adenoviral Carcinoembryonic antigen (CEA) vaccine

immunotherapeutic vaccine administered subcutaneously every 3 weeks for 3 doses, and then every 8 weeks for up to a year

Trial Locations (1)

20892

National Institutes of Health Clinical Center, Bethesda

All Listed Sponsors
lead

National Cancer Institute (NCI)

NIH

NCT03384316 - Multi-Targeted Recombinant Ad5 (CEA/MUC1/Brachyury) Based Immunotherapy Vaccine Regimen in People With Advanced Cancer | Biotech Hunter | Biotech Hunter