Comparison of Two Novel First-line Anti-Helicobacter Pylori Therapy

Esomeprazole ( Nexium )40 mg tid daily for 14 days in the high dose dual therapyarm and 40 mg bid daily for 7 days in the non-bismuth quadruple therapy

Amoxicillin 750 mg qid daily for 14 days in the high dose dual therapy and amoxicillin 1 g bid daily for 7 days in the non-bismuth quadruple therapy

clarithromycin 500 mg bid daily for 7 days in the non-bismuth quadruple therapy

Metronidazole (Flagyl) 500 mg tid daily for 7 days in the non-bismuth quadruple therapy