Selective Estrogen Receptor Modulators to Enhance the Efficacy of Viral Reactivation With Histone Deacetylase Inhibitors

PHASE2CompletedINTERVENTIONAL
Enrollment

31

Participants

Timeline

Start Date

April 26, 2018

Primary Completion Date

December 4, 2018

Study Completion Date

July 27, 2023

Conditions
HIV Infections
Interventions
DRUG

Tamoxifen

20 mg orally

DRUG

Vorinostat

400 mg orally

DRUG

Antiretroviral drugs

Participants will receive antiretroviral drugs provided by their own doctors. Antiretroviral drugs will not be provided by the study.

Trial Locations (15)

19104

Penn Therapeutics, CRS, Philadelphia

20005

Whitman-Walker Health CRS, Washington D.C.

27401

Greensboro CRS, Greensboro

27599

Chapel Hill CRS, Chapel Hill

35294

Alabama CRS, Birmingham

45219

Cincinnati Clinical Research Site, Cincinnati

60611

Northwestern University CRS, Chicago

80045

University of Colorado Hospital CRS, Aurora

90035

UCLA CARE Center CRS, Los Angeles

90502

Harbor-UCLA CRS, Torrance

94110

Ucsf Hiv/Aids Crs, San Francisco

30308-2012

The Ponce de Leon Center CRS, Atlanta

02114

Massachusetts General Hospital CRS (MGH CRS), Boston

07103

New Jersey Medical School Clinical Research Center CRS, Newark

00935

Puerto Rico AIDS Clinical Trials Unit CRS, San Juan

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT03382834 - Selective Estrogen Receptor Modulators to Enhance the Efficacy of Viral Reactivation With Histone Deacetylase Inhibitors | Biotech Hunter | Biotech Hunter