460
Participants
Start Date
February 21, 2018
Primary Completion Date
January 23, 2023
Study Completion Date
March 22, 2023
Reducing Antibiotics treatment duration
Antibiotics should be stopped from day 3 to 7 if respiratory cultures are negative and the patients fulfill a set of stringent clinical criteria signifying cardiopulmonary stability for 48 hours. If the respiratory cultures are positive, patients who fulfill the same set of clinical criteria should have their antibiotics stopped from day 5 to 7.
Standard Antibiotics treatment duration
Participants in the control (long duration) arm will receive standard care, which is antibiotic treatment for at least 8 days with the exact duration decided by the primary physician.
Civil Hospital, Kathmandu
Patan Academy of Health Science, Patan Hospital, Kathmandu, Patan
National University Hospital, Singapore, Singapore
Tan Tock Seng Hospital, Singapore
Khon Kaen Hospital, Khon Kaen
Srinagarind Hospital, Khon Kaen
Sunpasitthiprasong Hospital, Ubon Ratchathani
Collaborators (1)
Medical Research Council
OTHER_GOV
Department for International Development, United Kingdom
OTHER_GOV
Mahidol Oxford Tropical Medicine Research Unit
OTHER
University of Oxford
OTHER