120
Participants
Start Date
January 31, 2016
Primary Completion Date
June 30, 2017
Study Completion Date
June 30, 2018
Nutritional supplementation
Daily consumption of Tramiprosate (100 mg) for 1 year
Educational training
16 educational lessons (twice a week): basic principles of different cognitive domains (e.g. memory, attention, perception) and educational DVD viewing.
Counselling on a brain-healthy diet
4 lessons on the principles of Mediterranean Diet lead by a nutritionist, aimed to teach how to include brain-healthy foods in daily diet (e.g. antioxidant, omega-3 fatty acids and vitamins). Each participant will receive the educational material presented.
Physical exercise training
80 sessions of physical exercise supervised by a Fitness Training Expert with the aim of achieving 150 minutes of moderate-intensity physical activity per week
Computerized cognitive training
16 cognitive training sessions (twice a week) supervised by a psychologist, aimed to improve Attention, Processing speed, Memory, Social skills and Intelligence using BrainHQ (www.brainhq.com).
Ospedale San Raffaele, Milan
IRCCS Centro San Giovanni di Dio Fatebenefratelli, Brescia
Ospedale San Raffaele
OTHER
Istituto Di Ricerche Farmacologiche Mario Negri
OTHER
IRCCS Centro San Giovanni di Dio Fatebenefratelli
OTHER