162
Participants
Start Date
March 19, 2018
Primary Completion Date
September 24, 2024
Study Completion Date
September 24, 2024
Sildenafil 20 MG
Sildenafil, 20mg three times daily for 3 month period.
Placebo Oral Tablet
Placebo manufactured to look like Sildenafil 20 MG
Pulse wave velocity
Vascular pulse measurement at the radial, brachial, femoral, and carotid arteries are taken using a tonometer probe.
Carotid artery compliance and stiffness
An echocardiogram is done by using a probe placed on the skin.
Pressure wave reflection
Carotid pulse measurement taken using a tonometer probe
University of Iowa Hospitals and Clinics, Iowa City
National Institutes of Health (NIH)
NIH
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eric A. Hoffman
OTHER