Cooled Radiofrequency vs. Hyaluronic Acid to Manage Knee Pain

NACompletedINTERVENTIONAL
Enrollment

177

Participants

Timeline

Start Date

December 7, 2017

Primary Completion Date

February 8, 2019

Study Completion Date

July 20, 2020

Conditions
Osteoarthritis of the Knee
Interventions
DEVICE

Cooled Radiofrequency

Delivery of energy to ablate sensory nerves via cooled radiofrequency probe.

OTHER

Hyaluronic Acid Injection

Delivery of hyaluronic acid into knee by injection with needle to reduce knee pain.

OTHER

Crossover from Hyaluronic Acid Injection to Cooled Radiofrequency

Delivery of hyaluronic acid into knee by injection with needle to reduce knee pain. After 6 months, qualifying subjects in this group will have the option to crossover to receive cooled radiofrequency treatment.

Trial Locations (10)

16602

University Orthopedics Center, Altoona

16801

University Orthopedics Center, State College

19104

University of Pennsylvania, Philadelphia

22908

University of Virginia, Charlottesville

23235

Virginia iSpine Physicians, Richmond

29621

Piedmont Comprehensive Pain Management, Anderson

55905

Mayo Clinic, Rochester

70115

Ocshner Baptist Clinical Trials Unit, New Orleans

73013

Clinical Investigations, LLC, Edmond

83814

Lyman Medical Research, Coeur d'Alene

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Avanos Medical

OTHER