Outcome After Total Knee Arthroplasty Under General or Spinal Anesthesia

NACompletedINTERVENTIONAL
Enrollment

402

Participants

Timeline

Start Date

October 3, 2016

Primary Completion Date

December 22, 2018

Study Completion Date

December 3, 2019

Conditions
Knee OsteoarthritisArthropathy of Knee JointKnee Pain ChronicRheumatoid ArthritisAnesthesia
Interventions
PROCEDURE

Spinal anesthesia with tourniquet

Operation is done under spinal anesthesia and surgical tourniquet is used.

PROCEDURE

Spinal anesthesia without tourniquet

Operation is done under spinal anesthesia and without the use of surgical tourniquet.

PROCEDURE

General anesthesia with tourniquet

Operation is done under general anesthesia and surgical tourniquet is used.

PROCEDURE

General anesthesia without tourniquet

Operation is done under general anesthesia and without the use of surgical tourniquet.

DRUG

Oxycodone by patient-controlled analgesia (PCA)

PCA device (CADD Legacy PCA Pump, Smiths Medical, Kent, UK) is programmed to give intravenous oxycodone in doses of 0.04 mg/kg (ideal body weight). The minimum time between doses is set to 10 minutes and no more than 4 doses per hour are allowed.

Trial Locations (1)

00029

Helsinki University Central Hospital, Peijas hospital, Vantaa

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Helsinki University Central Hospital

OTHER

collaborator

University of Helsinki

OTHER

collaborator

Finland

UNKNOWN

lead

Riku Antero Palanne

OTHER