Conversion of in Vitro Fertilization Cycles to Intrauterine Inseminations in Patients With a Poor Ovarian Response to Stimulation

NACompletedINTERVENTIONAL
Enrollment

462

Participants

Timeline

Start Date

January 10, 2018

Primary Completion Date

November 25, 2022

Study Completion Date

March 14, 2024

Conditions
Infertility
Interventions
PROCEDURE

IVF / IVF-ICSI

"In the IVF arm, oocyte retrieval is performed 36 hours after the HCG injection, in the operating room, under transvaginal ultrasound guidance, under local or general anesthesia. The procedure lasts about 20 minutes and the patients are discharged on the same day. The oocytes retrieved from the follicles are transported immediately to the lab for fertilization with the partner's sperm. Fertilization is done either via conventional IVF, or via ICSI, depending on the indication. Embryos are later transferred into the uterus on day 3 or day 5, under ultrasound guidance, in the outpatient department."

PROCEDURE

IUI

"In the conversion to IUI arm, IUI is performed 24 to 36 hours after ovulation trigger. The partner provides the sperm on site on the morning of the insemination, which is performed in the outpatient department."

Trial Locations (32)

13005

UH La conception AP-HM, Marseille

14000

UH Caen, Caen

33520

Polyclinique Jean Villar, Bruges

35000

Clinique Mutualiste de la Sagesse, Rennes

UH Rennes, Rennes

37000

UHR Tours, Tours

37170

Clinique Léonard de Vinci, Chambray-lès-Tours

38000

UH Grenoble, Grenoble

44000

Clinique Jules Verne, Nantes

UH Nantes, Nantes

44800

Polyclinique de L'Atlantique, Saint-Herblain

49000

UH Angers, Angers

67000

UH Strasbourg, Strasbourg

92140

Antoine Béclère Hospital AP-HP, Clamart

92200

Clinique Pierre Cherest, Neuilly-sur-Seine

94000

IHC Créteil, Créteil

97110

UH Pointe-à-Pitre, Pointe-à-Pitre

561000

Lorient Hospital, Lorient

Unknown

Victor Pauchet Clinic, Amiens

UH Besançon, Besançon

Jean Verdier Hospital, APHP, Bondy

Cholet Hospital, Cholet

Sud Francilien Hospital, Corbeil-Essonnes

Tertre Rouge Clinic, Le Mans

UH Lille, Lille

UH Nîmes, Nîmes

Hospital of Orléans, Orléans

Cochin Hospital, APHP, Paris

Poissy Saint Germain en Laye Hospital, Poissy

UH Potiers, Potiers

UH Rouen, Rouen

UH Toulouse, Toulouse

All Listed Sponsors
lead

University Hospital, Angers

OTHER_GOV

NCT03362489 - Conversion of in Vitro Fertilization Cycles to Intrauterine Inseminations in Patients With a Poor Ovarian Response to Stimulation | Biotech Hunter | Biotech Hunter