NCT03361748 - Efficacy and Safety Study of bb2121 in Subjects With Relapsed and Refractory Multiple Myeloma | Biotech Hunter

Enrollment

149

Participants

Timeline

Start Date

December 13, 2017

Primary Completion Date

December 20, 2023

Study Completion Date

December 20, 2023

Conditions

Multiple Myeloma

Interventions

BIOLOGICAL

bb2121

: bb2121 consists of autologous T lymphocytes transduced with an anti-BCMA02 CAR lentiviral vector to express a chimeric antigen receptor targeting the human B cell maturation antigen (anti-BCMA CAR).

Trial Locations (48)

3000

Universitaire Ziekenhuizen Leuven, Leuven

10029

Local Institution - 109, New York

Mt. Sinai Medical Center, New York

24128

Local Institution - 602, Bergamo

Ospedali Riuniti di Bergamo, Bergamo

30322

Emory University, Atlanta

Local Institution - 103, Atlanta

31008

Clinica Universidad de Navarra, Pamplona

Local Institution - 701, Pamplona

37203

Local Institution - 101, Nashville

Sarah Cannon Research Institute, Nashville

40138

Azienda Ospedaliero Universitaria Di Bologna Policlinico, Bologna

Local Institution - 601, Bologna

44093

Centre Hospitalier Universitaire de Nantes - Hotel Dieu, Nantes

Local Institution - 401, Nantes

55905

Local Institution - 105, Rochester

Mayo Clinic, Rochester

59037

Centre Hospitalier Regional Universitaire de Lille-Hopital Calude Huriez Service des Maladies du Sang, Lille

Local Institution - 402, Lille

69120

Universitatsklinikum Heidelberg Medizinische Klinik Krehl-Klinik Haematologie, Onkologie, Rheumato, Heidelberg

Local Institution - 502, Heidelberg

72076

University of Tübingen, Tübingen

Local Institution - 503, Tübingen

75390

Local Institution - 104, Dallas

University of Texas Southwestern Medical Center, Dallas

94143

Local Institution - 108, San Francisco

University of California - San Francisco, San Francisco

97080

Universitatsklinikum Würzburg, Würzburg

Local Institution - 501, Würzburg

3290498

Jichi Medical University Hospital, Shimotsuke

02114

Local Institution - 107, Boston

02115

Dana Farber Cancer Institute, Boston

02214

Massachusetts General Hospital, Boston

02215

Local Institution - 106, Boston

07601

Hackensack University Medical Center, Hackensack

Local Institution - 102, Hackensack

B-3000

Local Institution - 201, Leuven

M5G 2M9

Local Institution - 301, Toronto

Princess Margaret Cancer Centre, Toronto

259-1193

Tokai University Hospital, Isehara

Local Institution - 803, Isehara City, Kanagawa

150-8935

Japan Red Cross Medical Center, Shibuya-ku

Local Institution - 801, Shibuya-ku

329-0498

Local Institution - 802, Shimotsuke

162-8666

Local Institution - 804, Shinjuku

Tokyo Women's Medical University Hospital, Shinjuku

08916

Hospital Universitari Germans Trias i Pujol Can Ruti, Badalona

Local Institution - 702, Badalona (Barcelona)