Discontinuation of Antidepressant Medication in Primary Care.

NACompletedINTERVENTIONAL
Enrollment

119

Participants

Timeline

Start Date

February 20, 2017

Primary Completion Date

August 1, 2019

Study Completion Date

August 1, 2019

Conditions
Antidepressants
Interventions
BEHAVIORAL

Supported Protocolized Discontinuation (SPD)

Patients who choose to discontinue their medication will make a personal tapering schedule with their GP based upon a discontinuation protocol with tapering suggestions. The protocol offers suggestions to taper within a maximum of 6 months describing all types of available dosages per antidepressant so individualized schedules can be constructed. In addition, they will be offered supportive meetings with the GP's mental health assistant. The assistant will receive basic information about discontinuation guidance, i.e. the information brochure, decision aid, discontinuation protocol and a short guideline how to organise consultations.

BEHAVIORAL

Mindfulness Based Cognitive Therapy (MBCT)

In addition to the SPD patients are offered Mindfulness Based Cognitive Therapy (MBCT) in homogeneous groups of patients willing to withdraw from their medication. MBCT will be offered according to the treatment protocol developed for recurrent depression, adaptated to the specific needs of patients discontinuing their antidepressant medication. The mindfulness courses will be provided by teachers qualifying the advanced criteria of the Association of Mindfulness Based Teachers in the Netherlands and Flanders. All teachers will receive additional training in using the specific study protocol at the start of the project.

Trial Locations (1)

6500HB

Radboud University Medical Centre for Mindfulness, Radboud University Nijmegen Medical Centre, Nijmegen

All Listed Sponsors
collaborator

Pro Persona Mental Health Care Foundation

OTHER

collaborator

Innovatiefonds Zorgverzekeraars

OTHER

lead

Radboud University Medical Center

OTHER

NCT03361514 - Discontinuation of Antidepressant Medication in Primary Care. | Biotech Hunter | Biotech Hunter