A Study of JNJ-63723283, an Anti-programmed Death-1 Monoclonal Antibody, Administered in Combination With Daratumumab, Compared With Daratumumab Alone in Participants With Relapsed or Refractory Multiple Myeloma

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

November 16, 2017

Primary Completion Date

October 24, 2018

Study Completion Date

November 19, 2021

Conditions
Multiple Myeloma
Interventions
DRUG

Daratumumab

Participants will receive daratumumab 16 milligram per kilogram (mg/kg) intravenously (IV) once every week for 8 weeks (Weeks 1 to 8); then once every other week for 16 weeks (Weeks 9 to 24); then once every 4 weeks (Week 25 onwards).

DRUG

JNJ-63723283

Participants will receive JNJ-63723283 240 mg IV during Week 1 on Cycle 1 Day 2, Cycle 1 Day 15, then every 2 weeks thereafter.

Trial Locations (13)

1090

UZBrussel, Brussels

2060

ZNA Stuivenberg, Antwerp

2650

UZA, Edegem

2930

Algemeen Ziekenhuis Klina, Brasschaat

8000

AZ St.-Jan Brugge-Oostende AV, Bruges

8500

Az Groeninge, Kortrijk

9000

UZ Gent, Ghent

31008

Clinica Univ. de Navarra, Pamplona

31096

Rambam Medical Center, Haifa

34362

Carmel Hospital, Haifa

91120

Hadassah Medical Center, Jerusalem

6423906

Sourasky Medical Center, Tel Aviv

08916

Hosp. Univ. Germans Trias I Pujol, Badalona

All Listed Sponsors
lead

Janssen Research & Development, LLC

INDUSTRY

NCT03357952 - A Study of JNJ-63723283, an Anti-programmed Death-1 Monoclonal Antibody, Administered in Combination With Daratumumab, Compared With Daratumumab Alone in Participants With Relapsed or Refractory Multiple Myeloma | Biotech Hunter | Biotech Hunter