Pilot Study of Biomarkers of Response to Immune Checkpoint Blockade in Metastatic Melanoma

CompletedOBSERVATIONAL
Enrollment

5

Participants

Timeline

Start Date

November 2, 2017

Primary Completion Date

June 17, 2022

Study Completion Date

June 17, 2022

Conditions
Melanoma
Interventions
OTHER

F-FDG PET/CT

F-FLT PET uses a thymidine analogue that accumulates in proliferating tissue. Proliferating tissue could include malignant lesions or immune cells. In this study, FLT PET/CT will be utilized as a molecular imaging tool to detect immune activation after administration of immune checkpoint blockade with pembrolizumab or nivolumab.

Trial Locations (1)

53792

University of Wisconsin Carbone Cancer Center, Madison

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

University of Wisconsin, Madison

OTHER

NCT03356470 - Pilot Study of Biomarkers of Response to Immune Checkpoint Blockade in Metastatic Melanoma | Biotech Hunter | Biotech Hunter