Acceptance and Preference of Lidocaine Gel Compared to Injection Anesthesia After Non Surgical Periodontal Treatment

PHASE4CompletedINTERVENTIONAL
Enrollment

94

Participants

Timeline

Start Date

December 5, 2017

Primary Completion Date

November 2, 2018

Study Completion Date

November 2, 2018

Conditions
Periodontitis
Interventions
DRUG

Lidocaine Hydrochloride 1% Gel

Cylinder vials with 1.7 g gel containing 34 mg lidocaine (1 g gel contains 20 mg lidocaine) will be used. Application of the gel into the periodontal pockets or the sulcus according to summary of product characteristics (SmPC). A total dose of 40 mg lidocaine should not be exceeded.

DRUG

Articaine hydrochloride/epinephrine (adrenaline) hydrochloride

Cylinder vials with 1.7 ml solution for injection containing 68 mg articaine and 0.0102 mg epinephrine (1 ml contains 40 mg articaine and 0.006 mg epinephrine) will be used. Infiltration anesthesia for the upper jaw and infiltration or nerve block anesthesia for the lower jaw with articaine solution for injection according to SmPC. Adults can be treated with up to 7 mg articaine per kg of body weight per treatment session.

Trial Locations (5)

14197

Charité - Universitätsmedizin Berlin Charité Centrum Zahn-, Mund- und Kieferheilkunde CC 3, Berlin

24105

Universitätsklinikum Schleswig-Holstein, Klinik für Zahnerhaltungskunde und Parodontologie, Kiel

35033

Universitätsklinikum Giessen und Marburg GmbH, Standort Marburg, Marburg

91341

Praxis Dr. Heckel, Röttenbach

97070

Praxis Dr. Petersilka, Würzburg

All Listed Sponsors
collaborator

Anfomed GmbH

INDUSTRY

lead

Chemische Fabrik Kreussler & CO GmbH

INDUSTRY

NCT03354312 - Acceptance and Preference of Lidocaine Gel Compared to Injection Anesthesia After Non Surgical Periodontal Treatment | Biotech Hunter | Biotech Hunter