Non-inferiority of Lower Dose Calcium Supplementation During Pregnancy

PHASE3CompletedINTERVENTIONAL
Enrollment

22,000

Participants

Timeline

Start Date

November 30, 2018

Primary Completion Date

November 3, 2022

Study Completion Date

December 16, 2022

Conditions
Pregnancy Related
Interventions
DIETARY_SUPPLEMENT

Daily 500 mg elemental calcium as calcium carbonate

Pregnant women in this arm will be provided and counselled to take three tablets, one containing 500 mg elemental calcium as calcium carbonate and 2 placebo supplements daily (total of 500 mg daily). The supplements in India will also contain 83.3 IU each of vitamin D3, for a total of 250 IU daily. No vitamin D3 will be given in Tanzania.

DIETARY_SUPPLEMENT

Daily1500 mg elemental calcium as calcium carbonate

Pregnant women in this arm will be provided and counselled to take three tablets each containing 500 mg elemental calcium as calcium carbonate daily (total of 1500 mg daily) as currently recommended by the World Health Organization. The supplements in India will also contain 83.3 IU each of vitamin D3, for a total of 250 IU daily. No vitamin D3 will be given in Tanzania.

Trial Locations (3)

Unknown

St. John's Research Institute, Bangalore

Africa Academy for Public Health, Dar es Salaam

Ifakara Health Institute, Dar es Salaam

All Listed Sponsors
collaborator

St. John's Research Institute

OTHER

collaborator

Ifakara Health Institute

OTHER

collaborator

Africa Academy for Public Health

OTHER

lead

Harvard School of Public Health (HSPH)

OTHER

NCT03350516 - Non-inferiority of Lower Dose Calcium Supplementation During Pregnancy | Biotech Hunter | Biotech Hunter