969
Participants
Start Date
April 1, 2016
Primary Completion Date
April 30, 2019
Study Completion Date
July 31, 2020
Trans-Dot point-of-care test
"Training set participants will be recruited and receive investigations for TB. Blood samples will also be collected from them for performance of ELISAs and laboratory-based TransDot tests. These blood samples will be drawn at baseline, week 8 and week 24 at end of treatment for confirmed TB cases and at baseline for non-TB cases.~Test set participants will be recruited and receive investigations for TB. A POC TransDot test will be performed on fingerprick blood at baseline, and at week 8 and week 24 in participants on TB treatment, as well as a laboratory based TransDot test on serum at baseline. The week 8 and week 24 TransDot tests will be used to investigate the test's utility as an indicator of treatment response."
Stellenbosch University, Cape Town
University of Namibia, Windhoek
LINQ Management GmbH, Berlin
European Research and Project Office GmbH, Saarbrücken
Armauer Hansen Research Institute, Addis Ababa
Medical Research Council The Gambia, Banjul
Makerere University, Kampala
The European & Developing Countries Clinical Trials Partnership Association (EDCTP), The Hague
Leiden University Medical Center (Academisch Ziekenhuis Leiden, LUMC), Leiden
London School of Hygiene and Tropical Medicine, London
Armauer Hansen Research Institute, Ethiopia
OTHER
Medical Research Council Unit, The Gambia
OTHER
Leiden University Medical Center
OTHER
Makerere University
OTHER
London School of Hygiene and Tropical Medicine
OTHER
European and Developing Countries Clinical Trials Partnership (EDCTP)
OTHER_GOV
LINQ Management GMBH
UNKNOWN
Prof Gerhard Walzl
OTHER