Deep Brain Stimulation with LIFUP for Mild Cognitive Impairment and Mild Alzheimer's Disease

NACompletedINTERVENTIONAL
Enrollment

2

Participants

Timeline

Start Date

November 10, 2018

Primary Completion Date

March 31, 2023

Study Completion Date

October 1, 2023

Conditions
Brain ImagingMild Cognitive ImpairmentAlzheimer DiseaseDeep Brain Stimulation
Interventions
DEVICE

Excitation

Administration of LIFUP, a method of deep brain stimulation, according to excitation paradigms using the following parameters: Tone Burst Duration = 50ms; Pulse Repetition Frequency = 10Hz; ISPTA = 720 mW/cm2. Four treatments of thirty seconds each, with two-minute intervals between treatment (20 minutes, approximately)

DEVICE

Inhibition

Administration of LIFUP, a method of deep brain stimulation, according to inhibition paradigms using the following parameters: Tone Burst Duration = 50ms and Pulse Repetition Frequency = 10Hz. Four treatments of thirty seconds each, with two-minute intervals between treatment (20 minutes, approximately)

Trial Locations (1)

90095

UCLA Semel Institute, Los Angeles

All Listed Sponsors
lead

University of California, Los Angeles

OTHER

NCT03347084 - Deep Brain Stimulation with LIFUP for Mild Cognitive Impairment and Mild Alzheimer's Disease | Biotech Hunter | Biotech Hunter