25
Participants
Start Date
January 8, 2018
Primary Completion Date
October 3, 2022
Study Completion Date
October 12, 2022
Intervention Arm
RIPC stimulus will be applied prior to the first intervention visit, using a previously validated (for cardiac protection in HD patients) standard dose (four cycles of cuff inflation to the lower limb of the patient and inflating at 200mmHg for five minutes, with five minutes' deflation).
Control Arm
Sham procedure in which the blood pressure cuff will be applied to the lower limb and inflated to 40mmHg for five minutes and deflated for five minutes with the cycle repeated a total of four times prior to dialysis. To be administered on a monthly basis from the baseline visit to the year 1 visit.
London Health Sciences Centre, London
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
OTHER