175
Participants
Start Date
October 1, 2017
Primary Completion Date
August 31, 2019
Study Completion Date
December 31, 2021
Mean blood glucose
Mean of blood glucose values measures by continuous glucose monitoring from week 80 to week 164 of the PERL trial.
Blood glucose CV
Coefficient of variation of blood glucose values measures by continuous glucose monitoring from week 80 to week 164 of the PERL trial.
% time 70-180 mg/dL
Percent of time with blood glucose in the 70-180 mg/dL range as measured by continuous glucose monitoring from week 80 to week 164 of the PERL trial.
% time below 54 mg/dL
Percent of time with blood glucose below 54 mg/dL as measured by continuous glucose monitoring from week 80 to week 164 of the PERL trial.
% time above 180 mg/dL
Percent of time with blood glucose above 180 mg/dL as measured by continuous glucose monitoring from week 80 to week 164 of the PERL trial.
% time above 250 mg/dL
Percent of time with blood glucose above 250 mg/dL as measured by continuous glucose monitoring from week 80 to week 164 of the PERL trial.
MAGE (Mean amplitude of glucose excursions)
Mean amplitude of glucose excursions as measured by continuous glucose monitoring as measured by continuous glucose monitoring from week 80 to week 164 of the PERL trial.
LBGI (Low Blood Glucose Index)
Low blood glucose index as measured by continuous glucose monitoring from week 80 to week 164 of the PERL trial.
HBGI (High Blood Glucose Index)
High blood glucose index as measured by continuous glucose monitoring from week 80 to week 164 of the PERL trial.
Allopurinol
Oral allopurinol tablets administered in the PERL Clinical Trial
Placebo
Oral placebo tablets administered in the PERL Clinical Trial
ICAHN School of Medicine at Mount Sinai, New York
Albert Einstein College of Medicine / Montefiore Medical Center, The Bronx
SUNY Upstate Medical University, Syracuse
Emory University - Grady Memorial Hospital, Atlanta
Brehm Center for Diabetes Research / University of Michigan, Ann Arbor
Henry Ford Health System, Detroit
University of Minnesota, Minneapolis
Northwestern University Feinberg School of Medicine, Chicago
Washington University, St Louis
UT Southwestern Dallas, Dallas
Barbara Davis Center / University of Colorado Denver, Aurora
Virginia Mason Medical Center, Seattle
University of Washington, Seattle
Providence Sacred Heart Medical Center, Spokane
Joslin Diabetes Center, Boston
Unversity of Calgary, Calgary
University of Alberta, Edmonton
BC Diabetes, Vancouver
University of Toronto, Toronto
The Leona M. and Harry B. Helmsley Charitable Trust
OTHER
University of Minnesota
OTHER
University of Colorado, Denver
OTHER
University of Michigan
OTHER
Northwestern University Feinberg School of Medicine
OTHER
Albert Einstein College of Medicine
OTHER
Washington University School of Medicine
OTHER
University of Washington
OTHER
Providence Medical Research Center
OTHER
Joslin Diabetes Center
OTHER