Study of Peri-Articular Anaesthetic for Replacement of the Knee

PHASE3CompletedINTERVENTIONAL
Enrollment

533

Participants

Timeline

Start Date

March 29, 2018

Primary Completion Date

February 28, 2021

Study Completion Date

April 21, 2021

Conditions
Knee Osteoarthritis
Interventions
DRUG

Liposomal bupivacaine

266mg/20ml vial of EXPAREL

DRUG

Bupivacaine hydrochloride

100mg/20ml 0.5% bupivacaine hydrochloride. Branded or generic, must be plain (cannot contain adrenaline/epinephrine)

Trial Locations (11)

Unknown

The Royal Orthopaedic Hospital, Birmingham

Chapel Allerton Hospital, Leeds

Pilgrim Hospital, United Lincolnshire Hospitals NHS Trust, Lincoln

The Whittington Hospital, London

Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry

Rotherham Hospital, Rotherham

King's Mill Hospital, Sherwood Forest Hospitals NHS Foundation Trust, Sutton in Ashfield

Torbay Hospital, Torquay

Pinderfields Hospital - Mid Yorkshire, Wakefield

Yeovil District Hospital, Yeovil

York Teaching Hospital, York

All Listed Sponsors
collaborator

University of Oxford

OTHER

lead

University of Leeds

OTHER

NCT03326180 - Study of Peri-Articular Anaesthetic for Replacement of the Knee | Biotech Hunter | Biotech Hunter