Thoracic Spinal Versus Epidural Anesthesia for Nephrectomy in Obstructive/Restrictive Lung Disease Patients

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

November 1, 2017

Primary Completion Date

June 1, 2018

Study Completion Date

June 1, 2018

Conditions
NephrectomyLung DiseasesAnesthesia
Interventions
PROCEDURE

Thoracic Spinal Anesthesia

"Spinal anesthesia will be performed for patients of the TSA group at the T7-T8 intervertebral space, using a 27 G pencil point needle with an introducer (Braun Melsungen, Melsungen, Germany).~When correct placement is confirmed by the free flow of clear CSF, 1.5 ml of hyperbaric Bupivacaine 0.5% (7.5 mg) in addition to 0.5 ml Fentanyl (25 μg) \& 5 μg dexmedetomidine will be injected."

PROCEDURE

Thoracic Epidural Anesthesia

"Epidural anesthesia will be performed for patients of the TEA group at the T7-T8 intervertebral space, using the Prefix Custom Epidural Anesthesia Tray with an 18 G Tuohy epidural needle \& a 20 G epidural catheter.~Patients will initially receive 5-10 ml of a mixed preparation of 0.5% isobaric Bupivacaine with 2 μg Fentanyl per ml volume as a bolus dose via the epidural catheter, this will be followed by a continuous infusion of 5-10 ml/hr started 1 hour after the bolus dose \& continued throughout the procedure."

DRUG

Bupivacaine 0.5% (hyperbaric)

Neuro-axially injected

DRUG

Bupivacaine 0.5% (isobaric)

Neuro-axially injected

DRUG

Fentanyl

Neuro-axially injected

DRUG

Dexmedetomidine

Neuro-axially injected

Trial Locations (1)

Unknown

Kasr Al-Ainy Hospital, Cairo University, Cairo

All Listed Sponsors
lead

Nazmy Edward Seif

OTHER

NCT03324490 - Thoracic Spinal Versus Epidural Anesthesia for Nephrectomy in Obstructive/Restrictive Lung Disease Patients | Biotech Hunter | Biotech Hunter