Quadratus Lumborum Block vs Transversus Abdominis Plane Block for Post-cholecystectomy Analgesia

NACompletedINTERVENTIONAL
Enrollment

159

Participants

Timeline

Start Date

October 1, 2017

Primary Completion Date

March 1, 2018

Study Completion Date

March 15, 2018

Conditions
Laparoscopic Cholecystectomy
Interventions
OTHER

Quadratus lumborum block Group (QL)

20 mL of 0.375% isobaric bupivacaine for each side deposited at the posterior aspect of the quadratus lumborum muscle (QLB type 2) using ultrasound after induction of general anesthesia and 15 minutes before start of surgery

OTHER

Transversus abdominis plane Group (TAP)

20 mL of 0.375% isobaric bupivacaine for each side using ultrasound after induction of general anesthesia and 15 minutes before start of surgery

OTHER

Control group (C)

No intervention will be done

DRUG

Paracetamol infusion

Paracetamol infusion (15 mg.kg) will be given by intravenous infusion after induction of general anesthesia.

DRUG

Ketorolac analgesia

In PACU Ketorolac 30 mg ampoule will be given by intravenous infusion to all cases and then every 8 hours.

DRUG

fentanyl

With induction of general anaesthesia, fentanyl (1 microgram.kg) will be given. Intraoperatively, Fentanyl boluses (0.5 microgram.kg) will be given in case of increase in intraoperative mean arterial blood pressure or heart rate of more than 20% of baseline for longer than 5 minutes. Postoperatively, Fentanyl boluses (20 micrograms) will be given if VAS is more than 3 and it might be repeated after 30 minutes until VAS is ≤ 3.

Trial Locations (2)

050

Mansoura University, Faculty of Medicine, Al Mansurah

Mansoura University, Al Mansurah

All Listed Sponsors
lead

Mansoura University

OTHER

NCT03323684 - Quadratus Lumborum Block vs Transversus Abdominis Plane Block for Post-cholecystectomy Analgesia | Biotech Hunter | Biotech Hunter