119
Participants
Start Date
December 12, 2017
Primary Completion Date
July 29, 2023
Study Completion Date
September 29, 2023
Capsaicin
Participants will inhale aerosolized capsaicin with the goal of this inducing cough and an urge-to-cough.
Resistive respiratory loads
Participants will breath through a mouthpiece. Every 3-5 breaths in, a respiratory load will be applied. Participants will be asked to rate the magnitude of the load.
Event-related evoked potential using electroencephalography (EEG).
The study team will use EEG time-locked to a respiratory occlusion to measure the brain's response to respiratory sensation.
Fluoroscopic swallow evaluation
Participants will swallow various consistencies of barium under fluoroscopy (moving-picture x-ray) in order to assess swallowing safety and efficiency.
University of Florida Center for Movement Disorders and Neurorestoration, Gainesville
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
University of Florida
OTHER