Venetoclax and Chemotherapy as Frontline Therapy in Older Patients and Patients With Relapsed/Refractory ALL

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

82

Participants

Timeline

Start Date

October 30, 2017

Primary Completion Date

April 30, 2026

Study Completion Date

April 30, 2027

Conditions
Leukemia
Interventions
DRUG

Venetoclax

"Venetoclax is an inhibitor of Bcl-2. Bcl-2 is critical for keeping cancer cells alive.~By inhibiting Bcl-2, venetoclax promotes cancer cell death."

DRUG

Standard Chemotherapy

Standard treatment of chemotherapy is administered

Trial Locations (5)

60637

RECRUITING

University of Chicago, Chicago

77030

RECRUITING

MD Anderson Cancer Center, Houston

84143

RECRUITING

Intermountain LDS Hospital, Salt Lake City

02114

RECRUITING

Massachusetts General Hospital, Boston

02115

RECRUITING

Dana Farber Cancer Institute, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AbbVie

INDUSTRY

lead

Dana-Farber Cancer Institute

OTHER