Paraspinal Muscle Relaxation in Spine Surgery

NACompletedINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

February 1, 2016

Primary Completion Date

December 21, 2018

Study Completion Date

December 21, 2018

Conditions
Paraspinal Muscle Relaxation in Spine Surgery
Interventions
DRUG

Anesthesia with non-depolarizing NMBA Rocuronium

Non- depolarizing NMBA Rocuronium will be used until full paraspinal muscle Relaxation. Muscle relaxation during surgery will be performed using intraoperative boli intermediate duration non-depolarizing NMBA, rocuronium (0.3 mg/kg) until good surgical conditions are achieved.

DIAGNOSTIC_TEST

TOF measurement

TOF (Train-of-four) measurements will be performed at baseline 5 minutes after induction after the effect of succinylcholine will have run off. Moreover, TOF measurements will be performed 5 minutes after each rocuronium bolus

DIAGNOSTIC_TEST

MEP measurement

MEPs (motor evoked potentials) are routinely obtained after intubation and before surgery, then every 10min during the critical preparation and closing phases of surgery and every 5min during the correction phase. In addition MEPs will be measured after the administration of the NMBA rocuronium. Baseline values for amplitudes and latencies are obtained directly prior to the start of the correction phase of the surgery.

Trial Locations (1)

8008

University Hospital Balgrist, Zurich

All Listed Sponsors
lead

Balgrist University Hospital

OTHER

NCT03318718 - Paraspinal Muscle Relaxation in Spine Surgery | Biotech Hunter | Biotech Hunter