NCT03318094View on ClinicalTrials.gov

Role of Sympathetic Vasoconstriction on Insulin-Mediated Microvascular Recruitment and Glucose Uptake in Obesity

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

October 24, 2017

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2025

Conditions
Insulin ResistanceHealthyObesity
Interventions
DRUG

Phentolamine

Intrabrachial phentolamine will be given on the blocked day

OTHER

Saline

Intrabrachial saline will be given this day

DRUG

Sodium Nitroprusside

Intrabrachial sodium nitroprusside will be given this day to compare with phentolamine

Trial Locations (1)

37232

Autonomic Dysfunction Center, Nashville

All Listed Sponsors
lead

Vanderbilt University Medical Center

OTHER