Locating Biomarkers in OCD Through Behavioral Tasks

Not yet recruitingOBSERVATIONAL
Enrollment

20

Participants

Timeline

Start Date

March 31, 2026

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2026

Conditions
OCDObsessive-Compulsive Disorder
Interventions
BEHAVIORAL

Beads Task

Participants will be asked to make a series of decisions that involve combining information about the value and probability of potential rewards. Subjects will sit in front of a computer monitor and place their hand over a box with orange and blue button that they will be asked to press based on their idea of which one will be the majority in a jar full of orange and blue beads. This task should take 15-20 minutes to complete, not including EEG setup.

BEHAVIORAL

PROVOC Tasks

Three tasks will be developed collaboratively with the participant and independent evaluator that involve the participant being exposed to triggers that are considered by him/her impossible to confront without ritualizing. There will also be a similar process involving objects that should not cause any distress to be used as a control. Sessions will be videotaped with AFAR system concurrent to recording of LFPs from VS and scalp EEG.

Trial Locations (3)

15260

University of Pittsburgh, Pittsburgh

77030

Baylor College of Medicine, Houston

02912

Brown University, Providence

Sponsors
All Listed Sponsors
collaborator

Brown University

OTHER

collaborator

University of Pittsburgh

OTHER

collaborator

Butler Hospital

OTHER

lead

Baylor College of Medicine

OTHER