A Study to Evaluate the Efficacy and Safety of VX-150 in Treating Subjects With Pain Caused by Small Fiber Neuropathy

PHASE2CompletedINTERVENTIONAL
Enrollment

89

Participants

Timeline

Start Date

September 20, 2017

Primary Completion Date

October 12, 2018

Study Completion Date

November 8, 2018

Conditions
Small Fiber Neuropathy
Interventions
DRUG

VX-150

Participants received VX-150 1250 milligrams (mg) once daily (qd) orally for 6 weeks.

DRUG

Placebo

Participants received placebo matched to VX-150 for 6 weeks.

Trial Locations (34)

10029

The Mount Sinai Hospital, New York

10032

Columbia University Medical Center, New York

12208

Albany Medical Center- Neurology Group, Albany

14618

University of Rochester, Rochester

21287

The Johns Hopkins Hospital, Baltimore

24013

Carilion Clinic Neurology, Roanoke

27103

Carolinas Pain Institute, Winston-Salem

27514

University of North Carolina School of Medicine, Chapel Hill

27710

Duke Neurological Disorders Clinic, Durham

32806

Bioclinica Research - Orlando, Orlando

33351

Infinity Clinical Research, Sunrise

45459

Neurology Diagnostics, Inc, Dayton

52242

University of Iowa Hospitals and Clinics, Iowa City

62702

Southern Illinois University (SIU) School of Medicine, Springfield

63110

Washington University School of Medicine in St. Louis, St Louis

66160

University of Kansas Medical Center (KUMC), Kansas City

66210

International Clinical Research Institute (ICRI), Overland Park

71105

River Cities Clinical Research Center, Shreveport

74104

The Richter Clinic for Neurology and Neuro-Psychiatry, Tulsa

80113

Blue Sky Neurology, Englewood

85004

Xenoscience Inc. - 21st Century Neurology, Phoenix

85251

Phoenix Neurological Associates, Ltd., Phoenix

87131

University of New Mexico Hospital, Albuquerque

92093

University of California San Diego, La Jolla

92868

SDS Clinical Trials, Inc., Orange

93710

Neuropain Medical Center, Fresno

94063

Stanford University School of Medicine, Redwood City

94705

Sutter Health - Alta Bates Summit Medical Center - The Jordan Research & Education Institute, Berkeley

98105

University of Washington, Seattle

03756

Dartmouth-Hitchcock Medical Center (DHMC), Lebanon

08901

Robert Wood Johnson Medical School, New Brunswick

Unknown

Universitätsklinikum Würzburg, Würzburg

Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta, Milan

Maastricht UMC+, Maastricht

All Listed Sponsors
lead

Vertex Pharmaceuticals Incorporated

INDUSTRY

NCT03304522 - A Study to Evaluate the Efficacy and Safety of VX-150 in Treating Subjects With Pain Caused by Small Fiber Neuropathy | Biotech Hunter | Biotech Hunter