6
Participants
Start Date
August 30, 2018
Primary Completion Date
August 2, 2021
Study Completion Date
August 2, 2021
Lenalidomide 15mg
At commencement of study : Lenalidomide will commence at 15 mg daily for days 1-14 of each cycle. Maximum number of cycles = 16. This is a dose finding study so doses will be adjusted depending on toxicity assessment over the course of the study. Dose may vary from 5 mg -25 mg daily depending on dose escalation results and recommendation of safety committee
Brentuximab Vedotin 1.8 mg/Kg
At commencement of study : Brentuximab vedotin 1.8mg/kg IV on day 1, repeated every 21 days. Maximum number of cycles = 16. This is a dose finding study so doses will be adjusted depending on toxicity assessment over the course of the study. Dose may be either 1.2 mg/Kg q21 days or 1.8 mg/kg q21 days depending on dose escalation results and recommendation of safety committee
Peter MacCallum Cancer Centre, Melbourne
Peter MacCallum Cancer Centre, Australia
OTHER