A Study of Tocilizumab in Chinese Participants With Systemic Juvenile Idiopathic Arthritis (sJIA)

PHASE4CompletedINTERVENTIONAL
Enrollment

62

Participants

Timeline

Start Date

April 26, 2018

Primary Completion Date

September 4, 2021

Study Completion Date

August 5, 2022

Conditions
Juvenile Idiopathic Arthritis
Interventions
DRUG

Tocilizumab

Tocilizumab will be administered as per the schedule specified in the arm description.

DRUG

NSAIDs

Participants may receive NSAIDs up to the maximum recommended stable daily dose. Study protocol does not enforce any particular NSAID.

DRUG

CSs

Participants may receive CSs at a stable dose of 30 milligrams per day (mg/day) or 0.5 milligrams per kilogram per day (mg/kg/day), whichever is less. Study protocol does not enforce any particular CS.

DRUG

MTX

Participants may receive MTX at a stable dose of less than or equal to (\</=) 20 milligrams per square meter (mg/m\^2).

Trial Locations (10)

100020

Capital Institute of Pediatrics, Beijing

100045

Beijing Children's Hospital, Capital Medical University; rheumatism, Beijing

130021

The First Hospital of Jilin University, Changchun

200127

Shanghai Children's Medical Center; Renal rheumatology, Shanghai

201102

Children's Hospital of Fudan University, Shanghai

210000

Chilren's hospital of nanjing medical university; Rheumatoid immunology, Nanjing

310052

The Children's Hospibal ZheJiang University School of Medicine, Hangzhou

325000

The Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical College, Wenzhou

400014

Children's Hospital Chongqing Medical university, Chongqing

510120

Sun Yat-sen Memorial Hospital, Sun Yat-sen University; Pediatric Rheumatology division, Guangzhou

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY

NCT03301883 - A Study of Tocilizumab in Chinese Participants With Systemic Juvenile Idiopathic Arthritis (sJIA) | Biotech Hunter | Biotech Hunter