Evaluation of Maxillary and Mandibulary Nerve Blocks on Morphine Consumption

CompletedOBSERVATIONAL
Enrollment

92

Participants

Timeline

Start Date

July 25, 2017

Primary Completion Date

July 25, 2017

Study Completion Date

August 10, 2017

Conditions
Dento Facial Dysmorphism
Interventions
PROCEDURE

Maxillary and mandibular blocks

A Pajunk SonoPlex Stim needle 22G x 55 mm was used. For maxillary nerve block, needle was introduced next to the angle of the orbitae and the zygomatic ridge. The needle was sank until coming into contact of the temporal bone. It was then orientated to the controlateral nostril and sank of 1 cm. For mandibular block, needle was introduced in the pterygoid fossa under and perpendicularly to the zygomatic arch, and sank until the pterygoid process. The needle was then orientated towards controlateral orbitae and sank with neurostimulation. After a motor response at 0.6 milliampere (mA) and the disappearance of contraction at 0.3 mA, local mixture was injected. The mixing of local anesthesia was made of ropivacaine 5 mg/mL and clonidine 30 µg. Five mL were injected in every block for a total of 20 mL.

PROCEDURE

General anesthesia

Anesthesia was standardized and provided using intravenous administration of propofol and remifentanil. Patients were mechanically ventilated with a mixture of air (50/50), and desflurane or sevoflurane, or Target-controlled infusion (TCI) propofol. One to 5 mg/kg of methyl-prednisolone were administered to reduce inflammatory response.

Trial Locations (1)

69004

Hospices Civils de Lyon, Lyon

All Listed Sponsors
lead

Hospices Civils de Lyon

OTHER

NCT03299998 - Evaluation of Maxillary and Mandibulary Nerve Blocks on Morphine Consumption | Biotech Hunter | Biotech Hunter