Adoptive Cell Therapy Across Cancer Diagnoses

Tumor-infiltrating lymphocytes grown ex-vivo from resected from cancer tissue and reapplied to the patient via an intravenous infusion.

One treatment with ipilimumab (3 mg/kg) prior to tumor resection.

4 doses of nivolumab. Starting 2 days prior to TIL infusion and every 2 weeks hereafter.

2 MIE s.c. injection, after TIL infusion and continuing for 2 weeks

2 doses (60 mg/kg) prior to TIL infusion

5 doses (25 mg/m2) prior to TIL infusion