Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone

PHASE3RecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

May 3, 2018

Primary Completion Date

January 31, 2027

Study Completion Date

January 31, 2028

Conditions
Giant Cell Tumor of Bone
Interventions
DRUG

Zoledronic Acid

4 mg of zoledronic acid (Zometa) will be added to each bag of bone cement

Trial Locations (16)

15212

RECRUITING

Allegheny-Singer Research Institute, Pittsburgh

21287

RECRUITING

Johns Hopkins University Hospital, Baltimore

27157

RECRUITING

Wake Forest University, Winston-Salem

44195

RECRUITING

Cleveland Clinic, Cleveland

46202

RECRUITING

Indiana University, Indianapolis

52242

RECRUITING

University of Iowa, Iowa City

63110

RECRUITING

Saint Louis University, St Louis

66211

RECRUITING

University of Kansas, Overland Park

73104

RECRUITING

University of Oklahoma, Oklahoma City

90404

NOT_YET_RECRUITING

University of California - Los Angeles, Los Angeles

98195

RECRUITING

University of Washington, Seattle

110029

RECRUITING

All India Institute of Medical Science, New Delhi

02114

RECRUITING

Massachusetts General Hospital, Boston

02115

RECRUITING

Boston Children's Hospital, Boston

02215

RECRUITING

Beth Israel Deaconess Medical Center, Boston

H3G 1A4

RECRUITING

McGill University Health Centre, Montreal

All Listed Sponsors
collaborator

Orthopedic Research and Education Foundation

OTHER

collaborator

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

OTHER

collaborator

University of Iowa

OTHER

collaborator

Johns Hopkins University

OTHER

collaborator

McGill University Health Centre/Research Institute of the McGill University Health Centre

OTHER

collaborator

The Cleveland Clinic

OTHER

collaborator

Wake Forest University

OTHER

collaborator

University of Kansas

OTHER

collaborator

Indiana University

OTHER

collaborator

University of Oklahoma

OTHER

collaborator

Beth Israel Deaconess Medical Center

OTHER

collaborator

Boston Children's Hospital

OTHER

collaborator

American Academy of Orthopaedic Surgeons

OTHER

collaborator

Massachusetts General Hospital

OTHER

collaborator

All India Institute of Medical Sciences

OTHER

collaborator

University of Washington

OTHER

collaborator

University of California

OTHER

lead

St. Louis University

OTHER