A Comparison of Methods of Discontinuing Nasal CPAP in Premature Infants <30 Weeks Gestation

NACompletedINTERVENTIONAL
Enrollment

66

Participants

Timeline

Start Date

September 19, 2017

Primary Completion Date

March 1, 2019

Study Completion Date

March 31, 2019

Conditions
Apnea of PrematurityRespiratory Distress Syndrome
Interventions
DEVICE

Discontinue NCPAP after weaning pressures

After randomization, CPAP pressure will be weaned by 1 every 24hours as long as the subjects continue to meet stability criteria after each wean, until CPAP of 4. If after decrease in CPAP pressure, the subject meets CPAP failure criteria pressure will be increased back to the previous level and after stabilization for 24 hours weaning process will be started again. Once the subject meets stability criteria on CPAP of 4, NCPAP will be stopped and subject will be placed on nasal cannula (NC) according to unit guidelines (max 1 Liter flow, 30% FiO2).

DEVICE

Discontinue NCPAP without weaning pressures

After randomization, once the subject meets stability criteria, NCPAP will be stopped and subject will be placed on nasal cannula (NC) according to unit guidelines (max 1 Liter flow, 30% FiO2).

Trial Locations (1)

77030

The University of Texas Health Science Center at Houston, Houston

All Listed Sponsors
lead

The University of Texas Health Science Center, Houston

OTHER

NCT03292562 - A Comparison of Methods of Discontinuing Nasal CPAP in Premature Infants <30 Weeks Gestation | Biotech Hunter | Biotech Hunter