Trial of Nab-paclitaxel in Patients With Desmoid Tumors and Multiply Relapsed/Refractory Desmoplastic Small Round Cell Tumors and Ewing Sarcoma

PHASE2CompletedINTERVENTIONAL
Enrollment

69

Participants

Timeline

Start Date

May 9, 2017

Primary Completion Date

September 30, 2021

Study Completion Date

September 30, 2021

Conditions
Tumor, Desmoplastic Small Round Cell, AdultTumor, Desmoplastic Small Round Cell, ChildhoodSarcoma, EwingSarcomaDesmoid
Interventions
DRUG

nab paclitaxel

Subjects in the DT cohort will receive a maximum of three cycles. Subjects in the DSRCT and ES cohort will receive unlimited cycles until disease progression, the subject begins a new anticancer treatment, withdrawal of parent/guardian/subject consent/assent, parent/guardian/subject refusal, physician decision, toxicity that cannot be managed by dose delay or dose reduction alone or the study ends for any reason

Trial Locations (7)

41013

H.U. Virgen del Rocío, Seville

Unknown

H. de la Santa Creu i Sant Pau, Barcelona

H. Sant Joan de Déu, Barcelona

H.U. 12 de Octubre, Madrid

H.U.Niño Jesús, Madrid

H.U i Politècnic La Fe, Valencia

H.U. Miguel Servet, Zaragoza

All Listed Sponsors
lead

Grupo Espanol de Investigacion en Sarcomas

OTHER

NCT03275818 - Trial of Nab-paclitaxel in Patients With Desmoid Tumors and Multiply Relapsed/Refractory Desmoplastic Small Round Cell Tumors and Ewing Sarcoma | Biotech Hunter | Biotech Hunter