Closed Incision Negative Pressure Therapy Versus Standard of Care Surgical Dressing in Revision Total Knee Arthroplasty

NACompletedINTERVENTIONAL
Enrollment

294

Participants

Timeline

Start Date

December 5, 2017

Primary Completion Date

November 27, 2019

Study Completion Date

December 19, 2019

Conditions
Surgical WoundRevision Total Knee ArthroplastyWounds and InjuriesJoint DiseaseMusculoskeletal DiseaseProsthesis-Related InfectionsInfectionPostoperative ComplicationsPathologic Processes
Interventions
DEVICE

Closed Incision Negative Pressure Therapy (ciNPT)

Closed Incision Negative Pressure Therapy applied through a foam bolster with a wicking interface fabric that includes 0.019% ionic silver at 125 mmHg of negative pressure for 5-7 days.

DEVICE

Standard of Care Dressing

A standard silver-impregnated dressing applied to a closed surgical incision for 5-7 days post-operatively.

Trial Locations (17)

10003

New York University (NYU), New York

10021

Hospital for Special Surgery, New York

10032

Columbia University Medical Center/New York Presbyterian Hospital, New York

10075

Northwell Health - Lenox Hill Hospital, New York

11706

Northwell Health - SouthSide Hospital, Bay Shore

19104

University of Pennsylvania, Philadelphia

19107

Rothman Institute - Thomas Jefferson University Hospital, Philadelphia

27705

Duke University Medical Center, Durham

30084

Emory University Orthopedics & Spine Hospital, Tucker

32743

Virginia Commonwealth University, Richmond

33331

Cleveland Clinic, Weston

43054

Joint Implant Surgeons, New Albany

44195

Cleveland Clinic, Cleveland

65212

University of Missouri Health Care, Columbia

70006

LSU Health Science Center, New Orleans

77030

Houston Methodist Research Institute, Houston

97239

Oregon Health & Science University, Portland

All Listed Sponsors
collaborator

3M

INDUSTRY

lead

KCI USA, Inc

INDUSTRY

NCT03274466 - Closed Incision Negative Pressure Therapy Versus Standard of Care Surgical Dressing in Revision Total Knee Arthroplasty | Biotech Hunter | Biotech Hunter