NCT03272230 - Assessment of Apathy in a Real-life Situation, With a Video and Sensors-based System | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

September 6, 2017

Primary Completion Date

December 8, 2023

Study Completion Date

May 8, 2024

Conditions

ApathyBehavioral Variant Frontotemporal Dementia (bvFTD)DisinhibitionDepression - Major Depressive Disorder

Interventions

BEHAVIORAL

ECOCAPTURE

45 minutes observational session for tracking goal directed behavior into a waiting room equipped with video and sensor-based data acquisition system

BEHAVIORAL

Cognitive and Behavioral experimental tasks

Cognitive and Behavioral experimental tasks to explore additional frontal cognitive and behavioral dimensions and functions

DIAGNOSTIC_TEST

Neuropsychological assessment

STARKSTEIN APATHY SCALE (SAS) / DAS / MMSE / MADRS / EBI / MINI-SEA / FAB / HAD / MATTIS / HAYLING / STROOP / Verbal Span / Lexical verbal fluency / TMT / CDRS

BEHAVIORAL

ICM_APATHY_TASKS

Apathy experimental task

OTHER

MRI

T1 / T2 / rs-fMRI / MS-DWI

BIOLOGICAL

Neurohormonal mechanisms

Hormonal dosage / Diabetic dosage / Ionogramme dosage / Inflammatory dosage / Hepatic dosage / Lipidic dosage / Thyroid dosage

Trial Locations (1)

75013

Paris Brain Institute / ICM / Pitié-Salpêtrière Hospital AP-HP / CIC, Paris

All Listed Sponsors

collaborator

Brain Institute Paris (ICM)

UNKNOWN

collaborator

Pitié-Salpêtrière Hospital (AP-HP)

UNKNOWN

lead

Institut National de la Santé Et de la Recherche Médicale, France

OTHER_GOV