Lacosamide Effects on Alcohol Self Administration and Craving in Heavy Drinkers

Lacosamide titration was done to a target dose of 300mg. Participants took 100 mg of lacosamide once on day 1, 100 mg twice per day from day 2 through day 6 (200 mg daily total), on day 7 the lacosamide dose was increased to 150 mg twice daily (300 mg daily total), and on day 8 the participant took one dose of 150 mg.

Participants took a placebo oral capsule once on day 1, twice per day from day 2 to day 7, and once on day 8.